New 3D printing paper published

A new scientific article has been published in Biofabrication, presenting the conceptual development of growth-adaptive calcium phosphate cement implants for large paediatric cranial defects. The study focused on establishing a reproducible design and manufacturing workflow for patient-specific, resorbable skull implants that can accommodate ongoing cranial growth while maintaining structural coherence and manufacturability.

For this work, the authors used INNOTERE’s Plotter-Paste-CPC, which is based on the same innovative material technology as our clinically established INNOTERE Paste-CPC and INNOTERE 3D Scaffold products. Using CT-derived patient anatomy, CAD-based reconstruction, and additive manufacturing by material extrusion, the team developed a modular implant concept consisting of ten interlocking segments with S-shaped interfaces, integrated guidance structures, and a defined assembly strategy.

Although the work represents a proof-of-concept and does not yet include biomechanical or biological validation, it establishes an important methodological foundation for future growth-adaptive cranial implant systems. The publication further highlights the versatility of our calcium phosphate cement paste technology as a platform for advanced patient-specific implant design and additive manufacturing in regenerative medicine.