Phone: +49 351 2599 9410
Fax: +49 351 2599 9429
Next generation bone substitute biomaterials combine bioactive and bioresorbable material features and are expected to activate in vivo mechanisms of tissue regeneration and to facilitate the replacement of the implants by the regenerating tissue. The key element of this approach is to mimick the structural, physical and chemical properties of the natural tissue by combination of different groups of biomaterials.
Currently we are involved in a project aiming at the development of highly orientated, bioactive collagen scaffolds for the treatment of bone defects. The innovative material approach is based on combining the structural characteristics of the scaffolds to induce guided cell growth and the incorporation of bioactive microparticles to achieve bone formation and synchronization of the bone remodeling process. In this project, INNOTERE is mainly responsible for the investigation of new synthesis routes to produce calcium phosphate or silicate microparticles with defined size and chemical composition.